Unlocking the future of RNA therapeutics
Breakthrough RNA delivery technology for a new biotherapy era at the service of our clients and partners
Our fields of application
Gene therapy
Fast and transient expression of one or several protein(s) of interest in one shot. First in Human trial in 2026 (treatment of secondary lymphedema though the simultaneous expression of 2 factors)
Genome edition
All-in-One system for a transient expression of the CRISPR-Cas9 system : very low off-target risk. Proven efficiency for base editing approaches as well.
Cell reprogramming
Gentle for sensitive cells, but efficient in the delivery of several reprogramming factors at once. Proven efficiency in iPSC
Vaccination
Fast protein expression with no adverse immune responses. 500 times more powerful than LNP for Covid vaccination with an equivalent RNA dose.
Immunotherapy
Low immunogenicity. Multiple (up to 4) and large (up to 10 kb) RNA delivery allowing concomitant delivery of antigens, immunomodulatory molecules and more…
Your application
FlashRNA® may be the ideal solution for your project as well.
Let’s explore the potential together!
Our technology
FlashRNA® combines the efficient cell transfer function of a lentivirus with the RNA packaging system of a bacteriophage. This unique fusion brings together the best features of both systems, delivering unmatched performance for multi-RNA delivery in vitro and in vivo. A particle carrying an RNA of human origin, manufactured with a biological process.
The next mRNA gold standard
RNA-competent vector for next-generation advanced therapy drugs FlashRNA® is an innovative RNA delivery solution, and an alternative to the current technologies as it is proprietary and proven from 10 years of expertise.
Multiple & different RNA delivery
Thanks to its unique features, FlashRNA® can carry various RNA species at once.
Low immunogenicity
Because RNAs are of biological origin and encapsulated in a natural human cell membrane.
No genome insertion
Not a lentiviral vector any more! No reverse transcription, no integrase, for a completely safe solution.
Short-term & transient expression
Fast expression of the proteins of interest, with a duration of expression related to their half-life.
Highly efficient
A broad tropism and a capacity to modify any type of cells, even very sensitive ones.
Accelerate Innovation
Transform Cell & Gene Therapy with RNAlead
Our Mission
At RNAlead, our mission is to provide our partners with a proprietary RNA delivery technology that is powerful, versatile, and proven. We support our clients throughout their innovation journey — from early-stage research to clinical applications — with a turnkey solution designed to meet the evolving demands of modern gene and cell therapy. We are continuously optimizing our platform to enable targeted delivery to specific cell types in vivo, expanding its therapeutic potential and real-world impact.
Our Vision
We believe in a future where medicine is faster, more precise, and more accessible. With the unmatched versatility of our platform, we unlock a broad range of therapeutic applications with a bold ambition: to become the go-to technology for RNA delivery. Our goal is to accelerate access to next-generation treatments by offering our clients a true performance driver and a strategic advantage in the market.
Our team
A dedicated team of 7 passionate professionals, combining deep, cross-functional expertisein FlashRNA® technology and its R&D to GMP production process — built on a strong foundation of shared experience and a unified vision.
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Contact us
Do you have a project in mind? We’d love to hear from you!
CRISPRMED 2026
RNAlead will attend the next CRISPRMED conference in Copenhagen, Denmark This premier annual event shines a spotlight on critical breakthroughs and challenges in CRISPR medicine – from cutting-edge tools and delivery systems to safety, regulation, functional genomics, pre-clinical pipelines, and advances in clinical trials.
Advanced Therapies UK 2026
Meet RNAlead at the Advanced TherapiesCongress in London, March 17-18, 2026.
International Biotherapy Days 2026
International Biotherapy Days 2026 Meet RNAlead at the International Biotherapy Days in Toulouse Valentin Alsat and Alexandra Iché will attend […]